IndraLab

Statements


EIF3H activates CRC. 4 / 4
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"Taken together, these data suggest that EIF3H interacts with HAX1.To further determine whether HAX1 was a potential substrate that mediated EIF3H-promoted CRC progression, we first checked whether EIF3H could regulate HAX1 abundance."

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"Taken together, these results suggest that EIF3H/HAX1 axis promotes CRC tumorigenesis and metastasis."

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"Pittman ( Pittman et al., 2010 ) showed that increasing of eIF3h stimulates CRC growth which seems to be due to amplification of the 8q23 region."

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"EIF3H/HAX1 axis promotes CRC tumorigenesis and metastasis in mouse orthotopic cancer model."