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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP18 activates mutated KRAS. 1 / 1

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"These findings showed that reduced USP18 levels can antagonize growth of KRAS mutant lung cancers, Yet, destabilization of ISGylated proteins downstream of KRAS might also be responsible for the growth inhibition observed after USP18 loss."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...