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USP21 activates USP21. 1 / 2

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"In addition, it is likely that zygotic USP16 continues to play a role in balancing the genomic deposition of H2AK119ub1, because 1) the early zygotic expression of paternal Usp16 can partially rescue the developmental defects of maternal Usp16-deleted embryos; and 2) knockout of paternal Usp16 strengthens the effect of maternal Usp16 knockout and leads to complete preimplantation failure in the Usp16 embryos."

35640597

INDRA sources:

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USP21 activates USP21. 1 / 2

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