IndraLab

Statements


TP53 bound to it activates TP53. 2 / 2
| 2

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"Then, it enters the nucleus and directly binds p53 through its GST domain, disrupts the MDM2-p53 association, and thereby blocks MDM2 mediated ubiquitylation and degradation of p53 [XREF_BIBR]."

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"For example, it has been shown that DAXX interacts with p53 and promotes p53 dependent apoptosis."