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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

UCHL1 activates IFNG. 2 / 2

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"Interestingly, UCHL1 inhibition markedly inhibited IFN-gamma plus TNF-alpha-induced decrease of Bcl-2 and activation of caspase 3, indicating the suppression of IFN-gamma plus TNF-alpha-induced MSC apoptosis."

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"Here, we found that inhibition of UCHL1 suppressed IFN-gamma plus TNF-alpha-induced MSC apoptosis, and this effect was not dependent on p53, the known target protein of UCHL1."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...