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UCHL1 activates IFNG. 2 / 2

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"Interestingly, UCHL1 inhibition markedly inhibited IFN-gamma plus TNF-alpha-induced decrease of Bcl-2 and activation of caspase 3, indicating the suppression of IFN-gamma plus TNF-alpha-induced MSC apoptosis."

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"Here, we found that inhibition of UCHL1 suppressed IFN-gamma plus TNF-alpha-induced MSC apoptosis, and this effect was not dependent on p53, the known target protein of UCHL1."

29686406

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IndraLab

Statements

UCHL1 activates IFNG. 2 / 2

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