IndraLab

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USP18 activates FTO. 2 / 2
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"Moreover, USP18 upregulation significantly accelerates the proliferation and migration of bladder cancer cells by enhancing the FTO/PYCR1 pathway [ 10 ]."

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"These data indicated that USP18 mediated increase of FTO protein stability exacerbates BLCA progression by enhancing carcinogenic properties of the tumor cells."