IndraLab

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SCN1ANAT increases the amount of SCN1A. 2 / 2
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"Another way is represented by the specific silencing of the well-known SCN1A natural antisense transcript (NAT), named SCN1ANAT, which is transcribed by the opposite strand of SCN1A gene and that normally modulates the expression of the SCN1A mRNA."
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"Taken together, the results from the 3 sets of experiments indicate that SCN1ANAT mediated increase of SCN1A expression does not result from spurious qualities of one AntagoNAT, non specific chemistry effect, generalized transcriptional upregulation or class effect involving all sodium channels."
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