IndraLab

Statements


USP9X decreases the amount of SOX2. 3 / 3
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"Usp9x KD but not Usp34 KD (XREF_FIG) reduced SOX2 levels in both BRAF mutant A375, SK-Mel28 (XREF_FIG), and NRAS-mutant SK-Mel147 (XREF_FIG) melanoma cell lines."

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"Therefore, we examined whether USP9X KD would lead to decreased SOX2 levels."

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"USP9X KD also decreased SOX2 protein levels at the iMeLC stage, confirmed by western blotting (Figure 3K)."