IndraLab

Statements

PSMD14 inhibits RNF168. 2 / 2

| 2

reach

"POH1 is localized to sites of DSBs and can directly antagonize RNF8/RNF168, which collaborate to deposit K63-linked polyubiquitin chains at H2A-type histones in response to damage [129]."

32708614

➶

reach

"BRCC36 and POH1 antagonize the actions of RNF8 and RNF168, hydrolyzing the K63 linkages that promote 53BP1 recruitment."

23554604

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

PSMD14 inhibits RNF168. 2 / 2

INDRA sources:

Databases

Reading