IndraLab

Statements

Aloe emodin inhibits STAT1. 3 / 3
| 3
reach
"Moreover, AE inhibits the NF-kappaB and IFN regulatory factor 5 (IRF5)/signal transducer activator of transcription 1 (STAT1) and IRF4 and STAT6 signaling pathways [XREF_BIBR]."
29707159
reach
"Aloe-emodin reversed STAT1 mediated response of NS-1-modulated suppression, as previously reported : galectin-3 triggering cytokine like regulation to activate JAK-STAT cascade in IFN-gamma-deficient [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
24877694
reach
"Since galectin-3 exhibited cytokine-like regulatory actions via JAK/STAT pathways, aloe-emodin also restored NS1-inhibited STAT1-mediated antiviral responses in transfected cells ."
30542141