IndraLab

Statements

USP25 activates TRAF6. 4 / 4
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"Induction of USP25 by viral infection promotes innate antiviral responses by mediating the stabilization of TRAF3 and TRAF6."
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"In addition, Lin et al. found that USP25, a deubiquitinating enzyme similar to USP5, promotes IRF3 and NF-κB activation and subsequent type I interferon and proinflammatory cytokine production after viral infection by stabilizing TRAF3 and TRAF6 [82]."
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"USP25 also promotes the RNA virus-induced p65/p50 activity by stabilizing TRAF6 through a ubiquitin-independent mechanism."
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"USP25 has been shown to enhance the stability of TRAF3 and TRAF6 [XREF_BIBR]."
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