IndraLab

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USP41 activates cell population proliferation. 12 / 12
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"As shown in Figure 3, knockdown of USP41 suppressed the proliferation of MCF-7 and MDA-MB-231 cells (Figure 3A,3C)."
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"Our study suggested that USP41 knockdown inhibits proliferation and invasive ability of breast cancer cells."
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"It has been reported that USP41 promotes proliferation of lung cancer cells , as well as in other cancerous cell lines, through regulating the deubiquitination of the receptor for activated C kinase 1 (RACK1) and the epithelial-mesenchymal transition transcription factor (EMT-TF) Snail ."
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"In contrast, the overexpression of USP41 significantly enhanced the proliferation of MCF-7 cells and MDA-MB-231 cells (Figure 3B,3D)."
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"Likewise, the ectopic expression of Snail prevented the USP41 siRNA-mediated reduction of cancer cell proliferation, while knockdown of Snail inhibits proliferation by USP41 overexpression (Figure 6G,H)."
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"Overexpression of USP41 greatly enhanced BC colony-forming ability, proliferation, and migration."
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"In vitro experiments further revealed that the knockdown of ABHD12 and USP41 significantly inhibit the proliferation, invasion and migration of breast cancer cells."
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"Other study revealed that USP41 knockdown inhibited cell proliferation, cell migration, and increased cell apoptosis in lung cancer (Ji et al. 2021)."
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"In contrast, USP41 knockdown significantly inhibited BC colony-forming ability, proliferation, and migration."
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"Knockdown of USP41 Inhibits Migration and Proliferation of Breast Cancer Cells."
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"Overexpression of USP41 Enhances Migration and Proliferation of Breast Cancer Cells."
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"We found that USP41 upregulation enhanced the growth, proliferation, and invasion of BC cells."
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