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USP10 inhibits cell population proliferation. 15 / 15
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"Furthermore, the double knock-down of G3BP1 and USP10 rescued the inhibition of proliferation induced by G3BP1 depletion in HCT116 (XREF_FIG) and SK-MEL-5 cells (XREF_SUPPLEMENTARY)."
24998844
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"Furthermore, we provide evidence that USP10 inhibits cancer cell proliferation in cells with WT p53."
20096447
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"Consistent with its molecular activity, re-expression of USP10 suppressed NSCLC cell proliferation and migration while knockout of USP10 promoted NSCLC cell proliferation and migration."
34416231
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"On the other hand, reconstitution of USP10 in cells with USP10 downregulation inhibited cancer cell proliferation (XREF_FIG), suggesting the effect of USP10 knockdown is specific."
20096447
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"In contrast, overexpressing USP10 expression in MHCC97L and BEL-7402 cells reduced the cell proliferation."
30056112
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"The research by Yuan et al. demonstrated that USP10 inhibits cancer cell proliferation in wild-type p53 cells, but promotes tumorigenesis in a mutant p53 background (Yuan et al., 2010)."
30319415
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"We showed that loss or inhibition of USP10 not only suppressed the proliferation of imatinib sensitive and imatinib resistant cells in vitro but also inhibited the growth of imatinib sensitive and imatinib resistant xenografts in vivo."
31044085
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"Next, we treated infected THP-1 cells with a cell-permeable potent autophagy inhibitor, spautin-1.58 Spautin-1 promotes the degradation of BECN1 by inhibiting 2 USPs (ubiquitin-specific peptidases), USP10 and USP13, which target BECN1.58 Spautin-1 treatment of infected cells significantly decreased E. chaffeensis proliferation (Fig. 3B)."
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"Conversely, downregulation of USP10 inhibited cell proliferation (XREF_FIG and data not shown)."
20096447
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"As expected, USP10 over expression inhibited the proliferation of colon cancer cells with either a wildtype p53 or with p53-deficency."
24332849
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"The deubiquitinase USP10 restores PTEN activity and inhibits non small cell lung cancer cell proliferation."
34416231
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"Furthermore, we provide evidence that USP10 inhibits cancer cell proliferation in cells with WT p53."
20096447
sparser
"Conversely, downregulation of USP10 inhibited cell proliferation ( xref and data not shown)."
20096447
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"The reconstitution of USP10 inhibited the colony formation and cell proliferation of the CAKI-1 and CAKI-2 RCC cell lines."
35627217
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"Furthermore, USP10 inhibits tumor cell proliferation by increasing p53 levels in cells with wild‐type p53, but exacerbates tumorigenesis in tumor cells with mutant p53 background."
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