IndraLab

Statements

BAP1 inhibits epithelial to mesenchymal transition. 6 / 6
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"Additionally, BAP1 regulates EMT during trophoblast differentiation and invasion, while decreased BAP1 expression triggers EMT and enhances migration and invasion (27)."
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"In vitro, BAP1 inhibited proliferation and EMT."
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"This indicates that BAP1 function loss inhibits TGF-β secretion in PE, thus implying that BAP1 alterations affect the EMT and tumor immunoescape , although its clinical significance remains unknown."
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"Interestingly, focal adhesion was enriched in shBAP1#1 and shBAP1#2 samples (Figure 5), suggesting BAP1 might inhibit EMT in osteosarcoma."
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"BAP1 suppressed osteosarcoma cell growth and EMT."
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"One study on cervical cancer cell lines reported that BAP1 knockdown induced increases in N-cadherin and vimentin and a decrease in E-cadherin (which are hallmarks of EMT) and increased cell migration [91]."
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