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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

COPS6 decreases the amount of UBR5. 2 / 2

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"Furthermore, we found that UBR5 knockdown rescued all the effects induced by CSN6 silencing, indicating that CSN6 activates the CDK9 pathway to promote melanoma growth and metastasis by reducing the UBR5 level."

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"Next, western blot analysis demonstrated that CSN6 increased CDK9 expression and decreased UBR5 expression in a dose dependent manner in 293FT cells."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...