IndraLab

Statements

USP4 binds HUWE1. 10 / 12
3 | 7
reach
"For example, USP4 interacts directly with and deubiquitinates ARF binding protein 1 (ARF-BP1), leading to the stabilization of ARF-BP1 and subsequent reduction of p53 levels."
26411366
reach
"Furthermore, USP4 interacts directly with and deubiquitinates ARF-BP1, leading to the stabilization of ARF-BP1 and subsequent reduction of p53 levels [XREF_BIBR]."
25972356
reach
"USP4 negatively regulates p53 by binding to ARF-BP1 and deubiquitinates it thereby promoting ARF-BP1-dependent ubiquitination and degradation of p53."
29479529
reach
"USP4 interacts directly with and deubiquitinates ADP-ribosylatibon factor binding protein 1 (ARFBP1), which results in the stabilization of ARF-BP1 and the subsequent reduction of p53 levels."
27430936
biogrid
No evidence text available
21522127
reach
"USP4 has been recently described as a key regulator of p53 stability: USP4 interacts directly and deubiquitylates the E3 HUWE1 (ARF-BP1; MULE), resulting in reduced p53 levels [86]."
23712866
reach
"USP4 interacts directly with and deubiquitinates ARF-BP1, leading to the stabilization of ARF-BP1 and subsequent reduction of p53 levels."
21522127
biogrid
No evidence text available
21522127
biogrid
No evidence text available
21522127
reach
"USP4 also interacts directly with and deubiquitinates ARF-BP1, leading to the stabilization of ARF-BP1 and subsequent reduction of p53 levels."
28791349