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Reactive nitrogen species activates PRPF8. 1 / 1

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"Mutagenesis of active site residues C1 and H169 abolished the binding of cisplatin to the Prp8 intein.In addition to metal-containing inhibitors, reactive nitrogen species compounds (DEA NONOate at 1.2 mM and 12 mM) and Angeli's salt at 2 mM and 20 mM) were found to inhibit splicing of the C. neoformans Prp8 intein in an in vitro Prp8 intein splicing assay, whereas H 2 O 2 (.8 and 8 mM) did not ."

35211511

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Reactive nitrogen species activates PRPF8. 1 / 1

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