IndraLab

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RAET1E binds AS1. 7 / 7
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"According to both the data from GEPIA () and TCGA (), we unveiled that the expression of LINC01559, LINC00483, LINC01296, RAET1E-AS1 and PCED1B-AS1 was significantly high in STAD (stomach adenocarcinoma) tissues in contrast with normal gastric tissues (Fig. xref , Supplementary Fig. xref )."
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"We randomly selected hsa-miR-145-5p for further analysis; it had ceRNA relationships with four mRNAs (ITGB8, WNT11, BMPER, and RARRES3), two lncRNAs (RAET1E-AS1 and LOC102723591), and one circRNA (hsa_circ_0092630) (Fig. xref e)."
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"However, the role of the lncRNA RAET1E-AS1 in cell biology has not been explored."
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"Correlation analyses revealed that the expression levels of RAET1E-AS1, WNT11, and BMPER had significantly negative correlations with the expression level of hsa-miR-145-5p (Fig. xref g–i), while the other RNAs did not exhibit such relationships (Figure S xref C, D)."
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"Furthermore, the expression level of RAET1E-AS1 had a significantly positive correlation with the expression levels of WNT11 and BMPER (Fig. xref j, k)."
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"Finally, we found that overexpression of has-miR-145-5p in ASCs could significantly downregulated the expression levels of WNT11, BMPER, RAET1E-AS1, LOC102723591, and hsa_circ_0092630 (Fig. xref l)."
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"Moreover, we found that five lncRNAs (RAET1E-AS1, LOC102723591, LOC105373230, LOC112267883, and LINC02595) and five circRNAs (hsa_circ_0017534, hsa_circ_0092630, hsa_circ_0080906, hsa_circ_0075045, and hsa_circ_0080909) were significantly upregulated in O-ASCs, compared with Y-ASCs (Fig. xref c)."
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