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USP36 activates epithelial to mesenchymal transition. 3 / 3
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"Zhu et al. reported that the expression of ubiquitin specific proteases 36 (USP36), a member of deubiquitinating enzymes family, was induced in DKD in human and murine model and in HG-treated TECs, and the overexpression of USP36 enhanced EMT in TECs."
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reach
"Additionally, USP36 directly bound to and mediated the de-ubiquitination of DOCK4, whereas DOCK4 knockdown effectively abolished EMT induced by USP36 overexpression through suppressing Wnt/β-catenin signaling in TECs (Zhu et al., 2021)."
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reach
"The results revealed that DOCK4 knockdown effectively abolished USP36 overexpression-induced EMT through suppressing Wnt/β-catenin signaling pathway in TECs (Figures 5M,N)."
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