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USP4 activates CrkII. 2 / 2

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"These data indicate that USP4 positively regulates the ERK1/2-MAPK and CrkII signaling pathways via a CypA dependent process."

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"We demonstrated that USP4 drives HCC progression by stabilizing CypA through direct interaction and deubiquitination and thus constitutively activates the MAPK and CrkII signaling pathways."

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IndraLab

Statements

USP4 activates CrkII. 2 / 2

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