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YAP1 activates USP20. 1 / 1

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"Thus, the inhibition of Hippo-YAP1 pathway-related DUBs may directly enhance the ubiquitination and degradation of the YAP1 protein, which could be a promising strategy to disrupt the function of the Hippo-YAP1 pathway and inhibit the progression of BC.Our siRNA screening assay identified USP20 as a critical USP that regulates YAP1 stability and the malignant phenotype of BC."

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IndraLab

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YAP1 activates USP20. 1 / 1

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