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USP1 deubiquitinates TRAF6. 3 / 3
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"USP1 function as an oncogene by interacting with DNA repair signal through PCNA and FANCD2 [35], USP4 promote cancer progression by deubiquitinating TRAF2 and TRAF6 and thereby regulating the TGFβ signaling pathway [36]."
34545063
reach
"Our result showed that overexpressing USP1 remarkably attenuated TRAF6 ubiquitination (Figure 4D), suggesting that USP1 stabilizes TRAF6 by decreasing TRAF6 ubiquitination, therefore regulating NF-κB signaling."
36458391
reach
"Our data show that USP1 decreases TRAF6 ubiquitination."
36458391