IndraLab

Statements


AKT phosphorylates USP4 on S445. 3 / 3
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sparser
"AKT directly phosphorylates USP4 at Ser445, relocating nuclear USP4 to the cytoplasm and membrane with the help of 14-3-3 protein, as well as enhancing its stability and deubiquitinating activity."

reach
"AKT directly phosphorylates USP4 at Ser445, relocating nuclear USP4 to the cytoplasm and membrane with the help of 14-3-3 protein, as well as enhancing its stability and deubiquitinating activity."

sparser
"Further study showed that USP4 can be phosphorylated at its Ser 445 by activated protein kinase B (AKT) and bind to 14-3-3 isoforms to be exported from nucleus to cytoplasm and subsequently exert its deubiquitination capacity [ xref ]."