IndraLab

Statements

Tamoxifen inhibits MYD88. 4 / 4
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"Specific tamoxifen induced MyD88 deletion in intestinal epithelial cells protects against diet induced obesity, is associated with increased energy expenditure, improves glucose homeostasis, and reduces hepatic steatosis and whole-body fat mass by 30%."
27105827
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"To evaluate the role in vivo of MyD88 expression in cardiomyocytes, we generated Mer + MyD88flox +/+ mice in which tamoxifen treatment is expected to eliminate the MyD88 gene exclusively in cardiomyocytes."
30067739
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"Tamoxifen treatment induces MyD88 gene deletion in cardiomyocytes of double transgenic Mer + MyD88flox +/+ mice."
30067739
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"The intestinal MyD88 deletion is induced by a tamoxifen injection in adult animals before starting the dietary intervention (XREF_FIG)."
25476696