IndraLab

Statements


| 2

sparser
"K13 directly or indirectly interacted with MALT1 and in particular its protease domain, and may thus induce a conformational change in the protease domain that promotes MALT1 activation, for example, by rendering it accessible to monoubiquitination."

sparser
"K13 most likely promoted NF-κB activation by direct or indirect physical recruitment of MALT1, as K13 interacted with MALT1 but not with BCL10 upon co-expression of the proteins in 293 T cells ( xref )."