IndraLab

Statements

Hydroxychloroquine inhibits chb. 11 / 11
| 11
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"Conclusions:. These prospective data support that HCQ significantly reduces the recurrence of CHB below the historical rate by more than 50%, suggesting that this drug be prescribed for secondary prevention of fetal cardiac disease in anti-SSA/Ro-exposed pregnancies."
32674792
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"A retrospective review of several large databases suggests that hydroxychloroquine use during pregnancy may decrease the risk of CHB."
20089705
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"HCQ may reduce the odds of CHB occurrence in fetuses exposed to maternal anti-Ro and SSA Ab, especially in mothers who have already had a child with congenital heart block [XREF_BIBR]."
28386140
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"Preventative therapy with hydroxychloroquine (HCQ) reduces the recurrence rate of CHB in subsequent pregnancies by ~50%."
36686025
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"These prospective data support that HCQ significantly reduces the recurrence of CHB below the historical rate by> 50%, suggesting that this drug should be prescribed for secondary prevention of fetal cardiac disease in anti-SSA and Ro-exposed pregnancies."
32674792
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"HCQ may reduce the odds of CHB occurrence in fetuses exposed to maternal anti-Ro and SSA antibodies, especially in mothers who already had a child with CHB."
27457513
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"Izmirly et al. in a retrospective study firstly highlighted that HCQ significantly decreased the occurrence of CHB in patients having a previous affected child."
33415090
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"Hydroxychloroquine has been proposed to reduce neonatal morbidity and the recurrence risk of CHB XREF_BIBR in patients with SLE."
28955500
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"In conclusion, data from this prospective single-arm clinical trial support that HCQ reduces the recurrence of CHB in anti-SSA/Ro exposed pregnancies by more than half and should be considered for secondary prevention."
32674792
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"This case illustrates that HCQ does not invariably prevent CHB and is consistent with the clinical observation that this approach will not be effective in all anti-SSA/Ro exposed foetuses."
28598777
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"Thus, given biologic plausibility and observational data, a Phase II study was initiated to address whether HCQ reduces the recurrence of CHB below the historical rate of 18% (14)."
32674792