IndraLab

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Modified ATXN3 increases the amount of HSPA5. 1 / 1
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"To monitor polyQ protein toxicity, we used both BiP gene induction and XBP1 splicing as readouts and found that the expression of MJD CAG78 protein induced BiP transcription (XREF_FIG D) and XBP1S production (XREF_FIG E) in our MJD CAG78 cell model."