IndraLab

Statements

ITCH activates TNFAIP3. 2 / 2
1 | 1
reach
"ITCH mediates binding of TNFAIP3 and Tax1BP1 with substrates 17."
28842689
signor
"Here we demonstrate that the regulatory molecule tax1bp1 recruited the e3 ligase itch to a20 via two 'ppxy' motifs. Itch was essential for the termination of tumor necrosis factor receptor signaling by controlling a20-mediated recruitment and inactivation of rip1. (abstract)"
18246070