IndraLab

Statements

USP24 activates Neoplasm Metastasis. 3 / 3
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"After IL-6 was added to the M2 macrophages conditioned medium, this effect was rescued, indicating that the USP24 induced metastasis activity is due to upregulated IL-6, which can be expressed by M2 macrophages or cancer cells."
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"We previously revealed that USP24 promotes lung tumor metastasis and enhances IL-6 secretion in TAMs to contribute to an immunosuppressive TME (18, 19)."
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"These findings further implied that NF-kappaB is indeed involved in USP24 promoted metastasis."
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