IndraLab

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"Intrathecal Minocycline Suppresses Itch Related Behavior and Improves Dermatitis in a Mouse Model of AtopicDermatitis."

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"The results showed that the expression of microglial marker ionized calcium binding adaptor molecule-1 was significantly increased after 5% imiquimod treatment in cervical spinal cord dorsal horn (C3-C4), and the intrathecal microglial inhibitor minocycline or PLX5622 diet suppressed both spontaneous itch and microglial activation."