IndraLab

Statements


OTUB1 leads to the deubiquitination of YTHDF2. 5 / 5
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"OTUB1 decreases YTHDF2 ubiquitination through a noncanonical mechanism."

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"These results all suggested OTUB1 decreased YTHDF2 ubiquitination through the noncanonical mechanism."

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"Altogether, these data demonstrated OTUB1 decreased YTHDF2 ubiquitination by noncanonically repressing ubiquitin transfer to YTHDF2."

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"OTUB1 antagonizes YTHDF2 ubiquitination."

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"We demonstrate that OTUB1 represses YTHDF2 ubiquitination through a noncanonical mechanism, which is inhibiting ubiquitin transfer to YTHDF2."