IndraLab

Statements

USP11 activates BECN1. 3 / 3
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"Rong et al. [23] demonstrated that increased expression of USP11 in neurons after SCI promotes functional recovery after injury by stabilizing Beclin1."
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"Importantly, USP11 promotes autophagy activation by stabilizing Beclin 1, thereby leading to ferroptosis."
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"Furthermore, the deubiquitinating enzyme USP11 promotes autophagy-dependent ferroptosis by stabilizing BECN1, leading to ferroptosis-mediated spinal cord ischemia-reperfusion injury [163]."
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