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(+)-alpha-tocopherol inhibits NFKB1. 2 / 2
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"When Jurkat cells were treated with okac acid subsequent to the preincubation with vitamin E derivatives, only a-tocopheryl succinate but not any other vitamin E derivatives were found to inhibit the [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Vitamin E promotes a barrier function and anti-inflammatory responses by binding the regulatory domain of protein kinase Calpha (pkcalpha) (a regulator and antagonist of heart failure) and decreases the activation of NF-kb, a proinflammatory transcription factor, causing the generation of cytokines and chemokines and mast cell activation."
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