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BAP1 bound to ASXL1-MT inhibits cell differentiation. 2 / 2

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"The ASXL1-MT and BAP1 complex is not a simple growth-accelerator, but rather inhibits terminal differentiation of HSPCs toward granulocytes, macrophages, mast cells, and erythrocytes."

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"Together, these results indicate that the ASXL1-MT and BAP1 complex impairs terminal differentiation of HSPCs, except for differentiation toward monocytes."

30013160

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IndraLab

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BAP1 bound to ASXL1-MT inhibits cell differentiation. 2 / 2

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