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TNF increases the amount of KCNH2. 2 / 2

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"TNF-α was also shown to inhibit IKrcurrents in HEK293 cells and ventricular myocytes and to decrease the amount of mature hERG channels on the cell membrane."

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"Immunoblotting analysis demonstrated that HERG protein level was slightly higher in canine hearts with tachypacing induced CHF than in healthy hearts, and TNF-alpha slightly increased HERG protein level in CHF but not in healthy hearts."

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IndraLab

Statements

TNF increases the amount of KCNH2. 2 / 2

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