IndraLab

Statements

USP28 decreases the amount of TP53. 2 / 2

| 2

reach

"Conversely, depletion of USP28 resulted in significantly increased K48 ubiquitination and simultaneously diminished p53 level, which could be fully reversed by addition of recombinant USP28 (XREF_FIG)."

31982308

➶

reach

"Notably, USP28 knockdown cells had decreased expression of p53, p21 and p16 INK4a, suggesting that the effect of USP28 on cell proliferation was mediated by regulating the expression of p53, p21 and p16 INK4a."

30910399

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

USP28 decreases the amount of TP53. 2 / 2

INDRA sources:

Databases

Reading