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Dioscin inhibits RELA. 2 / 2

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"47 In our study, we found that LPS elevated MyD88 level and p‐p65/p65 value, which was reversed by Dioscin; however, overexpressed TLR4 attenuated the effect of Dioscin on diminishing MyD88 expression and p‐p65/p65 value in LPS‐treated H9c2 cells."

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"In addition, TLR4, myeloid differentiation primary response gene 88 (MyD88), p-IKKbeta, p-p65, and NF-kappaB p65 in nuclei levels were significantly reduced by dioscin."

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Dioscin inhibits RELA. 2 / 2

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