IndraLab

Statements

TRIM21 binds OTUD4. 3 / 3
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"After the affinity purification by UBL7, mass spectrum results showed that UBL7 interacted with TRIM21 and OTUD4 ( Figure 5 A)."
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reach
"Moreover, an interaction between exogenous myc-UBL7 and flag-TRIM21 or flag-OTUD4 was observed by coIP ( Figure 5 B)."
36943869
reach
"To comprehensively address the mechanism by which the interplay of TRIM21-mediated ubiquitylation and OTUD4-guided deubiquitylation regulates CD73 proteolysis, we conducted structural modeling of the interaction between CD73, TRIM21, and OTUD4 by integrated use of experimental data and docking simulations followed by experimental validation."
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