IndraLab

Statements

USP45 binds ERCC1 and ERCC4. 4 / 4
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sparser
"Upon UV exposure, USP45 interacts with ERCC1–XPF but the USP45 mutant (Asp25Ala, Glu26Ala) that is catalytically active but that cannot bind to ERCC1 failed to deubiquitinate ERCC1."
27827925
sparser
"USP45 interacts specifically with ERCC1–XPF via its N-terminal 61 residues."
25538220
sparser
"These data suggested that USP45 interacts directly with XPF–ERCC1 and not with SLX4."
25538220
sparser
"USP45 associates with the ERCC1–XPF endonuclease."
25538220