IndraLab

Statements


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"Lastly, Sommer et al. [ xref ] identified a basic motif (R625-K626-G627-K628) for mediating interactions of the membrane-proximal domain (F581-E642) of ADAM17 with phosphatidylserine lipids, as indicated by significant chemical shift perturbations in the presence of phosphorylserine."

sparser
"We recently presented evidence that a direct interaction of ADAM17 with externalized phosphatidylserine (PS) is required for the protease to exert its sheddase function [ xref ]."