IndraLab

Statements

USP22 decreases the amount of CDKN. 2 / 2

| 2

reach

"USP22 increases the expression of cyclin-dependent kinase inhibitor 1A (CDKI) including p21 and p27, and it decreases the expression of Rb protein in HNSCC cells [74,75,76]."

36613989

➶

reach

"A previous study demonstrated that USP22 could inhibit the transcription of the cyclin-dependent kinase inhibitor 1A (p21) gene by deubiquitinating the transcriptional regulator fructose-1,6-bisphosphatase (FBP1) (5)."

30675271

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

USP22 decreases the amount of CDKN. 2 / 2

INDRA sources:

Databases

Reading