IndraLab

Statements

USP3 inhibits TP53BP1. 3 / 3
| 3
reach
"53BP1 and RAP80 foci are also negatively regulated by USP3 catalytic activity [18,110,132,135,136]."
32708614
reach
"In addition, USP3 overexpression impaired the accumulation of downstream repair factors BRCA1 and 53BP1 at the damage sites in response to both UV and gamma irradiation."
24196443
reach
"Overexpression of USP3, while having no effect on retention of RNF8 at DSBs, abolished the IR induced focus formation of RNF168, RAP80, and 53BP1, indicating that it de-ubiquitylates RNF8 targeted substrates."
23847653