IndraLab

Statements

UCHL1 decreases the amount of Ubiquitin. 5 / 7
| 5
reach
"Co-IP experiments showed that TAZ could be modified by the wild-type ubiquitin chain and that its ubiquitin level could be downregulated by UCHL1."
37215988
reach
"Previously, we found that UCHL1 deficient testes of gad mice have reduced ubiquitin levels and are resistant to cryptorchid stress related injury."
15744022
reach
"On the other hand, UCH-L1 deficiency does reduce ubiquitin levels in the nervous system and this is accompanied by an up-regulation of lysosomal components."
22355774
reach
"Meanwhile, UCHL1 is associated with upregulation of the activity of the histone H1 kinase relevant CDK1‐cyclin B complex and decreased ubiquitin levels, 85 suggesting that UCHL1 is essential for the development of porcine oocytes."
36218038
reach
"Decreased UCHL1 protein levels cause a reduction in the amount of monomeric ubiquitin in neurons and induce damage of the UPS [27] ."
27613482