IndraLab

Statements


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"USP7 inhibition induces cell apoptosis and cell cycle G2/M arrest, and overcomes taxane resistance by inducing the protein degradation of PLK1, resulting in chromosome misalignment in mitosis."

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"The following is/are the supplementary data related to this article : 3.5 Abrogation of USP7 suppressed GC cell proliferation and cell cycle progression."

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"Concomitantly, USP7 downregulation significantly arrested the cell cycle, increasing the proportion of A375 cells in the G1 phase and decreasing the proportion in the S phase (XREF_FIG)."