IndraLab

Statements

USP7 inhibits cell cycle. 6 / 6
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"Concomitantly, USP7 downregulation significantly arrested the cell cycle, increasing the proportion of A375 cells in the G1 phase and decreasing the proportion in the S phase (XREF_FIG)."
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"Knockdown of either USP7 or PLK1 induces cell apoptosis and cell cycle G2/M arrest, resulting in reduced taxane resistance [111]."
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"Moreover, while USP7 inhibition did induce slight cell cycle shifts from S to G phase, this effect was similar in both TP53-WT and TP53-KO contexts (Supplemental Figure 7E)."
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"The results suggested that knockdown of USP7 increases the ratio of G2/M phase in the cell cycle in p53-mutated LSCC cell lines (Fig. 5A-D)."
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"The following is/are the supplementary data related to this article : 3.5 Abrogation of USP7 suppressed GC cell proliferation and cell cycle progression."
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"Overall, these data indicated that USP7 was overexpressed in GC and that USP7 overexpression may contribute to the poor survival outcome of GC patients.3.2 Abrogation of USP7 suppressed GC cell proliferation and cell cycle progression."
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