
IndraLab
Statements
CACNA1S activates mertansine. 1 / 1
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1
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"In the case of Ca V 1.1 (CACNA1S) alternative splicing of exon 29 generates a calcium conducting Ca V 1.1 e that enhances calcium influx and generates spontaneous calcium sparklets in muscle fiber during EC coupling, resulting in reduced force and enhanced endurance as observed in myotonic dystrophies DM1 and DM2 [XREF_BIBR, XREF_BIBR]."