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"We have also showed that CYLD C/S expression enhances angiogenesis in mouse skin carcinomas, 21 what constitutes a prominent feature of skin tumor progression."

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"Based on a previous study showing that CYLD regulates vascular endothelial cell migration and angiogenesis in HUVECs [XREF_BIBR], we hypothesized that CYLD may also promote angiogenesis in a CNV model."

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"We find that knockdown of CYLD expression significantly impairs angiogenesis in vitro in both matrigel based tube formation assay and collagen based 3-dimensional capillary sprouting assay."