IndraLab

Statements


STAMBP activates MC3R. 3 / 3
| 3

sparser
"MC3R and MC4R in these neurons can be activated by α-MSH or inactivated by AgRP to exhibit negative or positive energy balance, respectively [ xref ]."

sparser
"ACTH can activate all five receptor subtypes; of the melanocortins, only ACTH activates MC2R; ACTH as well as α-MSH, β-MSH and γ-MSH activate MC1R, MC3R, MC4R and MC5R, although with varying affinities."

sparser
"ACTH (1–39) or α-MSH can activate MC1R, MC3R, MC4R, and MC5R ( xref ), but MC2R can only be activated by ACTH and not by α-MSH or other analogs ( xref )."