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USP24 deubiquitinates MCL1. 5 / 5
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"In T-ALL, USP24 exhibits a negative association with the prognosis of T-ALL and stabilizes Mcl-1 protein by deubiquitylating MCL-1 via the USP24-MCL-1 axis."
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"On the other hand, USP24 can deubiquitinate MCL-1 to prevent its degradation via K48 ubiquitin protein, thereby stabilizing MCL-1 and maintaining the mitochondrial transmembrane potential of tumor cel[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In myeloma, USP24 may play a major role in deubiquitination of MCL-1."
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"Inhibition of USP9X and USP24 increases the ubiquitination of MCL-1 and decreases the level of MCL-1."
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"In acute lymphocyte leukemia, USP24 deubiquitinates Mcl-1 and promotes T-ALL cell survival, as depicted in Fig. 4 below.Gasdermin B (GSDMB) has been shown to promote the progression of bladder cancer [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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