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MYH9 binds USP22. 2 / 2
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"Furthermore, we performed co-IP assays in HEK-293T cells and found that MYH9 could interact with USP22, especially MYH9-S1943E, but not MYH9-S1943A (Fig. xref ; Supplementary Fig. xref )."
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"This study confirmed that the p‐MYH9/USP22 complex stabilizes HIF‐1α under normoxic conditions, providing a promising therapeutic target for HCC cells that have metastasized into the bloodstream following drug resistance."
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