IndraLab

Statements

Zinc atom inhibits NLRP3. 3 / 3
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"Another study also showed that Zn suppressed NLRP3 activation by inducing microglia autophagy and played a neuroprotective role in spinal cord injury (40)."
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"In conclusion, the present study demonstrated that HG induced NLRP3 inflammasome activation in HPMCs, whereas Zn treatment inhibited NLRP3 inflammasome activation by attenuating oxidative stress."
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"These results indicated that Zn inhibited NLRP3 inflammasome activation in the HG treated HPMCs by activating the Nrf2 antioxidant pathway and reducing the production of ROS."
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